Y-mAbs Therapeutics, Inc. ((“Y-mAbs”, NASDAQ:YMAB), a commercial-stage biopharmaceutical company focused on the development and commercialization of novel, antibody-based therapeutic products for the treatment of cancer, is pleased to announce the acceptance of two presentations at the International Society of Pediatric Oncology (“SIOP”) Virtual Annual Congress held October 21 through October 24, 2021.
DANYELZA® (naxitamab-gqgk)
The abstracts include the following oral presentation of DANYELZA, the Company’s approved therapy for the treatment of pediatric patients with relapsed or refractory high-risk neuroblastoma, which is currently also being evaluated for the treatment of osteosarcoma and other GD2-positive tumors:
- “Naxitamab treatment of refractory/relapsed high-risk neuroblastoma (R/R HR NB); subgroup analysis of updated efficacy and safety data for the registrational Phase II trial”, submitted by SJD Barcelona Children’s Hospital in Barcelona, Spain
Omburtamab
The abstracts also include the following poster presentation of omburtamab, the Company’s lead product candidate, which is currently being evaluated for the treatment of patients with CNS/Leptomeningeal metastasis from neuroblastoma, diffuse intrinsic pontine glioma (“DIPG”), and desmoplastic small round cell tumors (“DSRCT”):
- “Outcomes of intraventricular 131-I-8H9 and external beam radiotherapy in patients with medulloblastoma, ependymoma, and pineoblastoma,” submitted by Memorial Sloan Kettering Cancer Center (“MSK”) in New York
Researchers at MSK developed DANYELZA® and omburtamab, which are exclusively licensed by MSK to Y-mAbs. As a result of this licensing arrangement, MSK has institutional financial interests in the compounds.
