Liminal BioSciences Inc. (NASDAQ:LMNL) (“Liminal BioSciences” or the “Company”), today announced that the first subject has been dosed in the Company’s Phase 1a single ascending dose (“SAD”) randomized, open label, cross over clinical trial of fezagepras to evaluate the safety, tolerability, and pharmacokinetics of single ascending dose of fezagepras compared to Sodium Phenylbutyrate in healthy volunteers.
“This Phase 1a SAD clinical trial is designed as a head-to-head comparison with Sodium Phenylbutyrate to provide us with further data to determine if fezagepras is worth developing for one of the many potential indications where nitrogen scavenging is beneficial,” stated Bruce Pritchard, Chief Executive Officer of Liminal BioSciences. “Following completion of the Phase 1a SAD clinical trial we expect to have data which will support whether or not to continue developing fezagepras as a potential nitrogen scavenger therapy, and expect to provide an update on the outcome of this clinical trial in the third quarter of 2022.”
