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C4X Discovery Holdings Signed Exclusive Global License Worth up to $402M with AstraZeneca for the Development and Commercialization of NRF2 Activator Program

C4X Discovery Holdings plc (AIM: C4XD), a pioneering Drug Discovery company, has signed an exclusive worldwide licensing agreement with AstraZeneca worth up to $402 million1, for its NRF2 Activator program. AstraZeneca will develop and commercialize an oral therapy for the treatment of inflammatory and respiratory diseases with a lead focus on chronic obstructive pulmonary disease (COPD).

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European Official Says COVID-19 Booster Uptake Disappointing In The Region

Marco Cavaleri, the European Medicines Agency's (EMA) head of health threats and vaccines strategy, said the recent uptake of COVID-19 vaccine booster doses in the region has been "rather disappointing." The European average rate of receiving booster doses was only 29% in the groups considered to be at the highest risk.

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AstraZeneca to Present New Data Advancing Its Ambition to Redefine Care at the 2022 San Antonio Breast Cancer Symposium; Twelve Medicines and Potential New Medicines Will Be Featured in 55 Presentations

Data will show clinical opportunity in HR-positive advanced breast cancer for potential first-in-class AKT inhibitor capivasertib and next-generation oral SERD camizestrant. Enhertu data will reinforce potential to set new standards in HER2-targetable disease. Data for antibody drug conjugate datopotamab deruxtecan will demonstrate potential in HR-positive and triple-negative breast cancer.

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