New data indicates potential to expand the therapeutic window and improve safety compared to existing T-cell engagers
Tri-specific T-cell engager resulted in AML cell-specific cytotoxicity with minimal
First clinical observation of tumor localized CD40 activation provided by MP0317
No systemic or dose-limiting toxicities observed, a key parameter for CD40 agents
Dose escalation remains ongoing with study
SVB Leerink analyst Daina Graybosch downgrades Molecular Partners (NASDAQ:MOLN) from Outperform to Market Perform and lowers the price target from $30 to $8.